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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
21.21
Human Site:
Y277
Identified Species:
42.42
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
Y277
N
R
K
V
R
E
A
Y
L
Q
F
M
V
S
V
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
Y279
N
R
K
V
R
E
A
Y
L
Q
F
M
V
S
V
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
M249
C
T
A
Y
V
D
F
M
I
S
V
A
R
L
I
Dog
Lupus familis
XP_546737
807
92419
Y305
N
R
K
V
R
E
A
Y
L
Q
F
M
M
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
Y263
N
H
K
V
R
K
A
Y
L
E
F
M
T
S
V
Rat
Rattus norvegicus
P0C1T0
774
89178
Y272
S
H
R
V
R
E
A
Y
L
Q
F
M
T
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
M247
R
E
A
Y
L
Q
F
M
I
T
I
A
K
M
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
Y253
Y
K
K
V
R
E
A
Y
L
E
F
M
V
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
E350
S
R
D
Y
Y
L
K
E
S
S
A
N
D
R
R
Honey Bee
Apis mellifera
XP_392502
776
89056
L277
L
P
S
R
D
Y
Y
L
K
K
S
S
E
S
Q
Nematode Worm
Caenorhab. elegans
O16796
848
97043
A347
L
F
S
S
H
M
T
A
Y
R
K
Y
L
R
Q
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
K265
E
Y
F
L
N
T
E
K
Y
Q
K
V
Q
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
0
93.3
N.A.
73.3
73.3
N.A.
N.A.
0
N.A.
73.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
20
100
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
93.3
N.A.
13.3
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
50
9
0
0
9
17
0
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
9
0
0
0
0
0
0
9
9
0
% D
% Glu:
9
9
0
0
0
42
9
9
0
17
0
0
9
0
0
% E
% Phe:
0
9
9
0
0
0
17
0
0
0
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
9
0
0
0
17
% I
% Lys:
0
9
42
0
0
9
9
9
9
9
17
0
9
0
0
% K
% Leu:
17
0
0
9
9
9
0
9
50
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
9
0
17
0
0
0
50
9
9
9
% M
% Asn:
34
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
42
0
0
9
0
17
% Q
% Arg:
9
34
9
9
50
0
0
0
0
9
0
0
9
17
9
% R
% Ser:
17
0
17
9
0
0
0
0
9
17
9
9
0
59
0
% S
% Thr:
0
9
0
0
0
9
9
0
0
9
0
0
17
0
0
% T
% Val:
0
0
0
50
9
0
0
0
0
0
9
9
25
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
25
9
9
9
50
17
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _